Known Issues: Cost
While multisig is slightly more expensive, for securing large amounts of bitcoin it’s well worth it. You can see more about recent multisig improvements here.
Buying multiple hardware wallets is more expensive than buying one.
Fortunately, open-source paper wallet software, like SeedPicker, is now available to enable you to add seed(s) to your multisig quorum for recovery without having to purchase additional hardware wallets to get started (until/unless you need to perform emergency recovery).
Higher Transaction Fees
The more signatures in your transaction, the higher your transaction fees.
The good news is that segwit gives a witness discount for
p2wsh transactions, which has led to them being labelled “Unfairly Cheap”!